产品货号:
Z33872
中文名称:
ROCK1抗体
英文名称:
Anti-ROCK1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ROCK1 Antibody |
指标别名 | p160 ROCK 1;P160ROCK;PRO0435;ROCK1 |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ICC/IF,IP,FCM |
基因名称 | ROCK1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human ROCK1 |
实际分子量 | 158KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | ROCK1,also named as p160ROCK and NY-REN-35,belongs to the protein kinase superfamily and AGC Ser/Thr protein kinase family.ROCK1 phosphorylates and activates DAPK3,which then regulates myosin light chain phosphatase through phosphorylation of MYPT1 thereby regulating the assembly of the actin cytoskeleton,cell migration,invasiveness of tumor cells,smooth muscle contraction and neurite outgrowth.ROCK1 is required for centromere positioning and centromere-dependent exit from mitosis.It is necessary for apoptotic membrane blebbing.ROCK1 catalyzes the reaction:ATP + a protein = ADP + a phosphoprotein. |
Uniprot ID | Q13464 |
基因名全称 | Rho associated coiled-coil containing protein kinase 1 |
蛋白名全称 | Rho-associated protein kinase 1 |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100ICC/IF Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Immunocoprecipitation 1:20 Flow cytometry (FCM) 1:20 |
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